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The Effects of in ovo Nanocurcumin Administration on Oxidative Stress and Histology of Embryonic Chicken Heart | ||
| Poultry Science Journal | ||
| مقاله 5، دوره 5، شماره 2، دی 2017، صفحه 105-111 اصل مقاله (509.61 K) | ||
| نوع مقاله: Original Paper | ||
| شناسه دیجیتال (DOI): 10.22069/psj.2017.12357.1231 | ||
| نویسندگان | ||
| A Araghi1؛ A Nazaktabar1؛ R Sayrafi1؛ A Salehi2؛ H Golshahi3؛ M Jahanbakhsh2؛ S Seifi* 1 | ||
| 1Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran | ||
| 2Department of Food Safety and Hygiene, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran | ||
| 3Department of Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran | ||
| چکیده | ||
| This study was designed to evaluate the effects of nanocurcumin (NC) on oxidative stress and histology of embryonic chicken heart. NC was injected into the yolk of 4-day-old embryonic eggs at one of three doses: 10 ppm (NC10 group), 100 ppm (NC100 group), and 1000 ppm (NC1000 group). The control group received normal saline. Oxidative stress in heart tissue was evaluated by measuring malondialdehyde (MDA) concentration, glutathione (GSH) content, and ferric reducing antioxidant power (FRAP). Serum lipids and cardio-histolopathogy were also measured. There were no significant differences in GSH, FRAP, and MDA levels between the control and treatment groups (p > 0.05). The serum lipid profile was altered in the NC100 group, with reduced levels of triglyceride (TG) (p < 0.01) but higher levels of HDL-c (p < 0.01) compared to the control. Heart histology was similar between NC10 and NC100 treatments compared to the control group. However, heart sections in NC1000 revealed focal areas of disrupted cardiac muscles and mild infiltration of mononuclear inflammatory cells between muscle fibers. It was concluded that NC at a concentration of 100 ppm did not damage heart tissues in chicken embryo and could be used as a valuable molecule for cardiovascular disease prevention. | ||
| کلیدواژهها | ||
| Nanocurcumin؛ Oxidative stress؛ Chicken embryo | ||
| مراجع | ||
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Abe C, Uto Y, Kawasaki A, Noguchi C, Tanaka R, Yoshitomi T, Nagasaki Y, Endo Y & Hori H. 2014. Evaluation of the in vivo antioxidative activity of redox nanoparticles by using a developing chicken egg as an alternative animal model. Journal of Controlled Release, 182: 67-72. DOI: 10.1016/j.jconrel.2014.03.015 Akila G, Rajakrishnan V, Viswanathan P, Rajashekaran K & Menon VP. 1998. Effects of curcumin on lipid profile and lipid peroxidation status in experimental hepatic fibrosis. Hepatology research, 11: 147-157. Anand P, Kunnumakkara AB, Newman RA & Aggarwal BB. 2007. Bioavailability of curcumin: problems and promises. Molecular pharmaceutics, 4: 807-818. DOI: 10.1021/mp700113r Bisht S, Feldmann G, Soni S, Ravi R, Karikar C, Maitra A & Maitra A. 2007. Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy. Journal of Nanobiotechnology, 5: 1-18. DOI: 10.1186/1477-3155-5-3 Benzie IF, Strain JJ. 1996. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Analitical Biochemistry, 239:70–76. Chen CC, Hsieh MS, Hsuuw YD, Huang FJ, & Chan WH. 2010. Hazardous effects of curcumin on mouse embryonic development through a mitochondria-dependent apoptotic signaling pathway. International Journal of Molecular Sciences, 11: 2839-2855. DOI: 10.3390/ijms11082839 Ding Q, Niu T, Yang Y, Guo Q, Luo F & Qian Z. 2014. Preparation of curcumin-loaded poly(ester amine) nanoparticles for the treatment of anti-angiogenesis. Journal of Biomedical Nanotechnology, 10: 632-641. DOI: 10.1166/jbn.2014.1829 Flora G, Gupta D & Tiwari A. 2013. Preventive efficacy of bulk and nanocurcumin against lead-induced oxidative stress in mice. Biological Trace Element Research, 152: 31-40. DOI: 10.1007/s12011-012-9586-3 Ganiger S, Malleshappa HN, Krishnappa H, Rajashekhar G, Rao VR & Sullivan F. 2007. A two generation reproductive toxicity study with curcumin, turmeric yellow, in Wistar rats. Food and Chemical Toxicology, 45: 64-69. DOI: 10.1016/j.fct.2006.07.016 Ghada Z. 2005. Effect of curcumin, mixture of curcumin and piperine and curcum (turmeric) on lipid profile of normal and hyperlipidemic rats. Egyptian Journal of Hospital Medicine, 21: 145-161.
Ghosh S, Banerjee S & Sil PC. 2015. The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update. Food and Chemical Toxicology, 83: 111-124. DOI: 10.1016/j.fct.2015.05.022 Gibson XA, Shartava A, McIntyre J, Monteiro CA, Zhang Y, Shah A &Goodman SR. 1998. The efficacy of reducing agents or antioxidants in blocking the formation of dense cells and irreversibly sickled cells in vitro. Blood, 91: 4373-4378. Hermann M, Mahon MG, Lindstedt KA, Nimpf J & Schneider WJ. 2000. Lipoprotein receptors in extraembryonic tissues of the chicken. Journal of Biological Chemistry, 275: 16837-16844. DOI: 10.1074/jbc.M000163200 Huang FJ, Lan KC, Kang HY, Liu YC, Hsuuw YD, Chan WH & Huang KE. 2013. Effect of curcumin on in vitro early post-implantation stages of mouse embryo development. European Journal of Obstetrics & Gynecology and Reproductive Biology, 166: 47-51. DOI: 10.1016/j.ejogrb.2012.09.010 Jain K, Sood S & Gowthamarajan K. 2013. Modulation of cerebral malaria by curcumin as an adjunctive therapy. The Brazilian Journal of Infectious Diseases, 17: 579-591. DOI: 10.1016/j.bjid.2013.03.004
JiangHua S, ChunYan Y, HaiYing Z, Jian W, FenXiang H, BingZhuang Y & XiangWei L. 2013. Effects of curcumin on buffalo embryonic development in vitro. Paper presented at the Buffalo Bulletin. Kakkar V & Kaur IP. 2011. Evaluating potential of curcumin loaded solid lipid nanoparticles in aluminium induced behavioural, biochemical and histopathological alterations in mice brain. Food and Chemical Toxicology, 49: 2906-2913. DOI: 10.1016/j.fct.2011.08.006 Kakkar V, Mishra AK, Chuttani K & Kaur IP. 2013. Proof of concept studies to confirm the delivery of curcumin loaded solid lipid nanoparticles (C-SLNs) to brain. International Journal of Pharmaceutics, 448: 354-359. DOI: 10.1016/j.ijpharm.2013.03.046 Kanai M, Imaizumi A, Otsuka Y, Sasaki H, Hashiguchi M, Tsujiko K, Matsumoto S, Isiguro H & Chiba T. 2012. Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers. Cancer Chemotherapy and Pharmacology, 69: 65-70. DOI: 10.1007/s00280-011-1673-1 Kidd PM. 1997. Glutathione: systemic protectant against oxidative and free radical damage. Alternative Medicine Review, 2: 155-176. Lao CD, Demierre MF & Sondak VK. 2006. Targeting events in melanoma carcinogenesis for the prevention of melanoma. Expert Review of Anticancer Therapy, 6: 1559-1568. DOI: 10.1586/14737140.6.11.1559 Liu CH & Chang FY. 2011. Development and characterization of eucalyptol microemulsions for topic delivery of curcumin. Chemical and Pharmaceutical Bulletin, 59: 172-178. DOI: 10.1248/cpb.59.172 Liu J, Chen S, Li L, Song L, Guo S & Huang S. 2013. Recent progress in studying curcumin and its nano-preparations for cancer therapy. Current Pharmaceutical Design, 19: 1974-1993. DOI: 10.2174/138161213805289327 McLaughlin J, Marliac JP, Verrette MJ, Mutchler MK, & Fitzhugh OG. 1963. The injection of chemicals into the yolk sac of fertile eggs prior to incubation as a toxicity test. Toxicology and Applied Pharmacology, 5: 760-771. DOI: 10.1016/0041-008X(63)90068-1 Menon VP & Sudheer AR. 2007. Antioxidant and anti-inflammatory properties of curcumin. Advances in Experimental Medicine and Biology, 595:105-125. DOI: 10.1007/978-0-387-46401-5_3 Nabavi SF, Nabavi SM, Ebrahimzadeh MA, Eslami S, Jafari N & Moghaddam HA. 2011. The protective effect of curcumin against sodium fluoride-induced oxidative stress in rat heart. Archives of Biological Sciences, 63: 563-569. DOI: 10.2298/ABS1103563N Nautiyal J, Banerjee S, Kanwar SS, Yu Y, Patel BB, Sarkar FH& Majumdar AP. 2011. Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells. International Journal of Cancer, 128: 951-961. DOI: 10.1002/ijc.25410 Nehra S, Bhardwaj V, Kalra N, Ganju L, Bansal A, Saxena S & Saraswat D. 2015. Nanocurcumin protects cardiomyoblasts H9c2 from hypoxia-induced hypertrophy and apoptosis by improving oxidative balance. Journal of Physiology and Biochemistry, 71: 239-251. Noiva RM, Menezes AC, Peleteiro MC. 2014. Influence of temperature and humidity manipulation on chicken embryonic development. BMC Veterinary Research, 10: 234. DOI: 10.1186/s12917-014-0234-3 Pourasgari F, Ahmadian S, Salmanian AH, Sarbolouki MN & Massumi M. 2009. Low cytotoxicity effect of dendrosome as an efficient carrier for rotavirus VP2 gene transferring into a human lung cell line. Molecular Biology Reports, 36: 105-109. DOI: 10.1007/s11033-007-9157-4 Rahimi HR, Mohammadpour AH, Dastani M, Jaafari MR, Abnous K, Ghayour Mobarhan M & Kazemi Oskuee R. 2016. The effect of nano-curcumin on HbA1c, fasting blood glucose, and lipid profile in diabetic subjects: a randomized clinical trial. Avicenna Journal of Phytomedicine, 6: 567-577. Ramsewak RS, DeWitt DL, & Nair MG. 2000. Cytotoxicity, antioxidant and anti-inflammatory activities of Curcumins I–III from Curcuma longa. Phytomedicine, 7: 303-308. DOI: 10.1016/S0944-7113(00)80048-3 Sadighara P, Jahed Khaniki G, Baseri E, Dehghani MH, Barin A & Mazaheri Nezhad Fard R. 2013. Effect of bisphenol A on the quality characteristics of meat in a chicken embryo model. Science International, 1: 375-378. DOI: 10.17311/sciintl.2013.375.378 Sankar P, Telang AG, Suresh S, Kesavan M, Kannan K, Kalaivanan R & Sarkar SN. 2013. Immunomodulatory effects of nanocurcumin in arsenic-exposed rats. International Immunopharmacology, 17: 65-70. DOI: 10.1016/j.intimp.2013.05.019 Sarbolouki MN, Alizadeh AM, Khaniki M, Azizian S & Mohaghgheghi MA. 2012. Protective effect of dendrosomal curcumin combination on colon cancer in rat. Tehran University Medical Journal, 69: 678-685.(In persian with English abstract) Satoskar RR, Shah SJ & Shenoy SG. 1986. Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation. International Journal of Clinical Pharmacology, Therapy, and Toxicology, 24: 651-654. Seifi S, Araghi A, Sayrafi R & Salehi A. 2015. Effects of rice bran oil on qualitative properties of heart and breast muscle tissues in chicken embryo model. International Food Research Journal, 22:1894-1897. Shaikh J, Ankola DD, Beniwal V, Singh D & Ravi Kumar MNV. 2009. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. European Journal of Pharmaceutical Sciences, 37: 223-230. DOI: 10.1016/j.ejps.2009.02.019 Soni KB & Kuttan R. 1992. Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers. Indian Journal of Physiology and Pharmacology, 36: 273-273. SPSS (Statistical Packages for the Social Sciences) 2006.SPSS for Windows Release 16.0. SPSS Inc. Chicago. Turley SD, Herndon MW & Dietschy JM. 1994. Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster. Journal of Lipid Research, 35: 328-339. Wang X, Jiang Y, Wang YW, Huang MT, Ho CT & Huang Q. 2008. Enhancing anti-inflammation activity of curcumin through O/W nanoemulsions. Food Chemistry, 108: 419-424. DOI: 10.1016/j.foodchem.2007.10.086 Wu JY, Lin CY, Lin TW, Ken CF & Wen YD. 2007. Curcumin affects development of zebrafish embryo. Biological and Pharmaceutical Bulletin, 30: 1336-1339. DOI: 10.1248/bpb.30.1336 Wyne KL & Woollett LA. 1998. Transport of maternal LDL and HDL to the fetal membranes and placenta of the Golden Syrian hamster is mediated by receptor-dependent and receptor-independent processes. Journal of Lipid Research, 39: 518-530. Xiao J, Sheng X, Zhang X, Guo M & Ji X. 2016. Curcumin protects against myocardial infarction-induced cardiac fibrosis via SIRT1 activation in vivo and in vitro. Drug Design, Development and Therapy, 10: 1267-1277. DOI: 10.2147/DDDT.S104925 Yallapu MM, Jaggi M & Chauhan SC. 2012. Curcumin nanoformulations: a future nanomedicine for cancer. Drug Discovery Today, 17: 71-80. DOI: 10.1016/j.drudis.2011.09.009 Yang KY, Lin LC, Tseng TY, Wang SC & Tsai TH. 2007. Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC–MS/MS. Journal of Chromatography B, 853: 183-189. DOI: 10.1016/j.jchromb.2007.03.010 | ||
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